C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A01K 67/027 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2301202
In accordance with the present invention, there are provided isolated mammalian TRAIL receptor proteins, antibodies thereto, therapeutic compositions, and nucleic acids encoding such. Bioassays and therapeutic methods employing invention DR5 and TRAIL-R3 proteins are also provided.
La présente invention se rapporte à des protéines mammifères isolées réceptrices de TRAIL, à des anticorps dirigés contre ces protéines, à des compositions thérapeutiques et à des acides nucléiques codant ces protéines. L'invention concerne également des dosages biologiques et des procédés thérapeutiques utilisant les protéines DR5 et TRAIL-R3 selon l'invention.
Alnemri Emad S.
Gowling Lafleur Henderson Llp
Idun Pharmaceuticals Inc.
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