C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/705 (2006.01) A61K 33/24 (2006.01) A61K 38/17 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2709463
The present invention relates to the use of a mutant TRAIL protein to treat various cancers in mammals. The invention provides a variant TRAIL protein, which has superior selectivity for the death receptor 5, for treating a mammal diagnosed with cancer.
La présente invention concerne l'utilisation d'une protéine TRAIL mutante pour traiter divers cancers chez des mammifères. L'invention concerne un variant de protéine TRAIL qui possède une sélectivité supérieure pour le récepteur de mort cellulaire (death receptor) 5, afin de traiter un mammifère chez qui a été diagnostiqué un cancer.
Cool Robbert Hans
de Jong Steven
de Ruijter Marieke
de Vries Emma Geertruida Elisabeth
Duiker Evelien Wilma
Academisch Ziekenhuis Groningen
Fundacio Privada Centre de Regulacio Genomica (crg)
Institucio Catalana de Recerca I. Estudis Avancats (icrea)
Kirby Eades Gale Baker
National University Of Ireland Galway
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