Trans-2-substituted-amido-hexahydrobenzo ¬a| quinolizines

Details Trans-2-substituted-amido-hexahydrobenzo ¬a| quinolizines Trans-2-substituted-amido-hexahydrobenzo ¬a| quinolizines

C - Chemistry, Metallurgy

07

D

260/271.5

C07D 471/04 (2006.01) C07D 455/03 (2006.01) C07D 455/06 (2006.01)

Patent

CA 1118422

Docket No. 11856 TRANS-2-SUBSTITUTED-AMIDO-HEXAHYDROBENZO [a] QUINOLIZINES ABSTRACT OF THE DISCLOSURE Disclosed are trans-2-substituted-amido-hexahydro- benzo[a]quinolizines represented by the formula: Image In the above formula, R1 and R2 are independently -H or -OCH3 or when taken together are Image , R3 is -H or -CH3 and R4 is CH3 , Image , Image , Image , Image , Image , Image , Image , Image , Image , Image , Image , Image or Image . These compounds, and their pharmacologically acceptable, non-toxic, acid addition salts are useful as anti-hypertensive agents.

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