Trans-chinnamic acid derivative and preparation method and...

Details Trans-chinnamic acid derivative and preparation method and... Trans-chinnamic acid derivative and preparation method and...

C - Chemistry, Metallurgy

07

C

C07C 39/19 (2006.01) A61P 35/00 (2006.01) C07C 57/44 (2006.01)

Patent

CA 2726419

A compound of formula(I)or its pharmaceutically acceptable salt, which is prepared by ring opening of osthol under basic condition. The compound of formula(I)or its pharmaceutically acceptable salt has activity of selectively inhibiting tumor cells and lower toxicity, and can be used for preparing anti-tumor drugs.

L'invention porte sur un composé de formule (I) ou son sel pharmaceutiquement acceptable préparé par ouverture de cycle d'osthol dans des conditions basiques. Le composé de formule (I) ou son sel pharmaceutiquement acceptable peut inhiber de façon sélective des cellules tumorales et présent une toxicité moindre et peut donc servir à préparer des médicaments antitumoraux.

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