Trans-pt (iv) complexes

Details Trans-pt (iv) complexes Trans-pt (iv) complexes

C - Chemistry, Metallurgy

07

F

C07F 15/00 (2006.01) A61K 31/295 (2006.01) A61K 31/555 (2006.01)

Patent

CA 2061759

Abstract of the Invention Trans-Pt(IV) compounds of general formula [PtX2Y2L1L2)] where X is halogen, Y is halogen, hydroxyl or carboxylate and each L is an amine ligand, providing L1 and L2 are not both NH3 are surprisingly active against cancer cells, in contrast to expectations that all trans-Pt compounds are inactive.

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