Trans-species transfer of apoptotic genes and transgenic...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/82 (2006.01) A01H 5/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2348705

The invention relates to trans-species transfer of apoptotic genes to plant cells, transgenic plants developed therefrom, and screening assays using these plants. The invention also relates to drug discovery screening methods utilizing transgenic plant cells. In addition, the invention relates to methods of identifying plant apoptotic pathway components utilizing non-plant proteins and nucleic acids.

L'invention concerne le transfert inter-espèces de gènes apoptotiques dans des cellules végétales, des plantes transgéniques obtenues par ce transfert et des procédés de sélection comprenant l'utilisation de ces plantes. L'invention concerne également des procédés de sélection comprenant l'utilisation de cellules végétales transgéniques en vue de d'identifier des médicaments. L'invention concerne en outre des procédés permettant l'identification des composants du mécanisme d'apoptose des plantes au moyen de protéines et d'acides nucléiques non végétaux.

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