Transacylases of the paclitaxel biosynthetic pathway

Details Transacylases of the paclitaxel biosynthetic pathway Transacylases of the paclitaxel biosynthetic pathway

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C07H 21/00 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12P 17/02 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2387971

Transacylase enzymes and the use of such enzymes to produce TaxolTM, related taxoids, as well as intermediates in the TaxolTM biosynthetic pathway are disclosed. Also disclosed are nucleic acid sequences encoding the transacylase enzymes.

Cette invention a trait à des enzymes, des transacylases en l'occurrence, ainsi qu'à leur utilisation aux fins de la production de Taxol ?TM¿, à des taxoïdes en rapport ainsi qu'à des intermédiaires de la voie biosynthétique du Taxol ?TM¿. L'invention concerne également des séquences nucléotidiques codant ces transacylases.

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