A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/5377 (2006.01) A61K 31/4184 (2006.01) A61K 31/42 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61K 31/496 (2006.01)
Patent
CA 2562763
Substituted benziomidozole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benziomidazole compounds, as well as pharmaceutical preparations therefore, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
La présente invention a trait à des composés de benzoimidazole substitués utiles en tant qu'agents anti-infection qui diminuent la résistance, la virulence, ou la croissance de microbes. L'invention a également trait à des procédés de fabrication et d'utilisation de composés de benzoimidazole substitués, ainsi qu'à des préparations pharmaceutiques de ceux-ci, par exemple, dans la réduction de la résistance aux antibiotiques et l'inhibition de films biologiques.
Alekshun Michael N.
Amoo Victor
Kim Oak K.
Verma Atul K.
Borden Ladner Gervais Llp
Paratek Pharmaceuticals Inc.
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