Transcription factor modulating compounds and methods of use...

A - Human Necessities – 61 – K

Patent

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A61K 31/4184 (2006.01) A61K 31/437 (2006.01) A61K 31/52 (2006.01) A61P 11/00 (2006.01) A61P 13/02 (2006.01) A61P 17/02 (2006.01) A61P 27/02 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2681813

Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of using substituted benzimidazole compounds, in, e.g., reducing virulence and infectivity, inhibiting biofilms and treating bacterial infections.

L'invention porte sur des composés de benzimidazole substitués utiles comme agents anti-infectieux qui diminuent la résistance, la virulence ou la croissance de microbes. L'invention porte également sur des procédés d'utilisation de composés de benzimidazole substitués, par exemple dans la réduction de la virulence et l'infectiosité, dans l'inhibition de biofilms et dans le traitement d'infections bactériennes.

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