C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/12 (2006.01) A61K 31/4184 (2006.01) A61K 31/4196 (2006.01) A61K 31/675 (2006.01) C07D 235/22 (2006.01) C07D 413/12 (2006.01) C07F 9/6506 (2006.01)
Patent
CA 2656157
Substituted benzoimidazole compounds useful as anti-infectives that decrease resistance, virulence, or growth of microbes are provided. Methods of making and using substituted benzoimidazole compounds, as well as pharmaceutical preparations thereof, in, e.g., reducing antibiotic resistance and inhibiting biofilms.
L'invention concerne des composés de benzoimidazole substitués qui sont utiles en tant qu'anti-infectieux qui diminuent la résistance, la virulence ou la croissance de microbes. L'invention concerne également des procédés de fabrication et d'utilisation de composés de benzoimidazole substitués, ainsi que de préparations pharmaceutiques les contenant, par exemple pour réduire la résistance aux antibiotiques et pour inhiber les films biologiques.
Alekshun Michael N.
Bartlett Victoria
Garrity-Ryan Lynne
Grier Mark
Kim Oak K.
Borden Ladner Gervais Llp
Paratek Pharmaceuticals Inc.
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