C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/85 (2006.01) A61K 31/70 (2006.01) A61K 38/02 (2006.01) A61K 48/00 (2006.01) C07K 14/71 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2225460
The invention features substantially pure DNA containing an endothelial cell- specific promoter sequence capable of directing endothelial cell-specific transcription of a polypeptide-encoding sequence or an antisense template to which it is operably linked. The invention also features methods for identifying compounds which inhibit or enhance endothelial cell growth.
L'invention concerne de l'ADN pratiquement pur contenant une séquence de promoteur spécifique de la cellule endothéliale, capable de diriger la transcription spécifique de la cellule endothéliale d'une séquence codant des polypeptides ou d'un gabarit non codant relié à ladite séquence. L'invention concerne également des procédés d'identification de composés inhibant ou amplifiant la croissance des cellules endothéliales.
Haber Edgar
Lee Mu-En
Patterson Winston Campbell
Kirby Eades Gale Baker
President And Fellows Of Harvard College
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