Transcutaneous in vivo activation of photosensitive agents...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61K 31/12 (2006.01) A61K 31/365 (2006.01) A61K 31/409 (2006.01) A61K 31/47 (2006.01) A61N 5/00 (2006.01)

Patent

CA 2144327

A method destroys or impairs target cells that have selectively accumulated a photosensitizing agent. The target cells are in the bloodstream of an intact animal, which bloodstream and animal further contain non-target cells. Radiation is applied tran- scutaneously to at least a portion of the intact animal at an intensity effective to impair or destroy selectively the target cells and to leave non-target cells relatively unimpaired. Target cells include leukemia cells, virus-containing cells, parasite-containing cells, and microorganisms such as bacteria, parasites and free viruses.

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