Transdermal administration of fentanyl and device therefor

Details Transdermal administration of fentanyl and device therefor Transdermal administration of fentanyl and device therefor

A - Human Necessities

61

K

167/159, 167/232

A61K 9/00 (2006.01) A61K 9/70 (2006.01) A61K 31/445 (2006.01) A61M 37/00 (2006.01)

Patent

CA 1245983

ARC 1232 ABSTRACT OF THE DISCLOSURE 7696-74 Transdermal delivery systems for delivery of fentanyl and its analgetically effective derivatives for extended periods of time are disclosed which deliver the base form of the drug at a rate of from 0.5 to 10 µg/cm2/hr for a substantial portion of their useful life. The systems can be from 5-100 cm2 in releasing surface and preferably employ an in-line amine resistant adhesive. Preferred rate controlled systems utilize an aqueous ethanolic gel to minimize drug content.

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