Transdermal administration of oxybutynin

A - Human Necessities – 61 – K

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Details

A61K 47/14 (2006.01) A61K 9/70 (2006.01) A61K 31/215 (2006.01) A61K 31/216 (2006.01) A61K 31/22 (2006.01)

Patent

CA 2132865

The present invention is directed to the transdermal administration of oxybutynin together with a suitable permeation en- hancer. The invention includes a transdermal drug delivery device comprising a matrix adapted to be placed in oxybutynin- and permeation enhancer-transmitting relation with the skin site. The matrix contains sufficient amounts of a permeation enhancer and of oxybutynin, in combination, to continuously administer to the skin for a predetermined period of time the oxybutynin to provide an effective therapeutic result. The invention is also directed to a method for the transdermal administration of a thera- peutically effective amount of oxybutynin together with a skin permeation- enhancing amount of a suitable permeation enhancer.

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