Transdermal administration system for estradiol

Details Transdermal administration system for estradiol Transdermal administration system for estradiol

A - Human Necessities

61

K

A61K 31/565 (2006.01) A61K 9/70 (2006.01) A61K 31/57 (2006.01)

Patent

CA 2095789

The adhesive plaster for the transdermal ad- ministration of estradiol or mixture estradiol/ proges- tin is composed of an impermeable carrier film and of an adhesive composition. The latter represents a matrix or reservoir layer and is composed of a solvent-based polyacrylate or polyisobutylene adhesive which contains a saturated or unsaturated fatty acid with 6 to 18 C atoms as permeability enhancer, estradiol or mixture estradiol/progestin as active substance and optionally propylene glycol as solvent. The adhesive plaster is used for the systemic administration of hormones in hormone replacement ther- apy for a time of at least 3 days.

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