Transdermal, alcohol-free, pharmaceutical compositions

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/565 (2006.01) A61K 9/12 (2006.01) A61K 47/08 (2006.01) A61M 11/04 (2006.01) A61P 5/30 (2006.01)

Patent

CA 2699630

An alcohol-free, transdermal drug delivery composition administered via a metered spray drug delivery device is described herein. The non-occlusive transdermal drug delivery composition includes a therapeutically effective amount of at least one physiologically active agent or prodrug thereof, an effective amount of at least one dermal penetration enhancer; and at least one non-volatile liquid. The transdermal drug delivery composition is administered to a dermal or mucosal surface of an animal needing the same using a metered spray device capable of delivering a fine spray of substantially uniform particle size to minimize the required drying time therefor.

Cette invention concerne une composition médicamenteuse transdermique sans alcool, administrée par un dispositif d'aérosol-doseur. La composition médicamenteuse transdermique non-occlusive comprend une quantité thérapeutiquement efficace d'au moins un agent physiologiquement actif ou son promédicament, une quantité efficace d'au moins un activateur de pénétration dermique ; et au moins un liquide non volatil. La composition médicamenteuse transdermique est appliquée sur le derme ou la muqueuse d'un animal nécessitant ce traitement à l'aide d'un dispositif d'aérosol-doseur capable de pulvériser une fine couche de particules sensiblement uniformes pour réduire la durée de séchage du produit.

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