A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/05 (2006.01)
Patent
CA 2176462
The present invention is for pharmaceutical compositions and a method of use for the transdermal delivery of N-[N-[5-[4(aminoiminomethyl)phenyl]-1- oxopentyl]-L-.alpha.-aspartyl]-L-phenylalanine or its esters and their pharmaceutically acceptable salts which are useful as platelet aggregation inhibitors. In formula (I), R can be independently hydrogen or alkyl having 1 to 6 carbon atoms.
L'invention porte sur des compositions pharmaceutiques et un mode d'utilisation en vue de l'administration transdermique de N-[N-[5-[4-(aminoiminométhyl)phényl]-1-oxopentyl]-L-.alpha.-aspartyl]-L-phénylalanine ou de ses esters et de leurs sels pharmaceutiquement acceptables, de formule (I), où R peut représenter indépendamment hydrogène ou alkyle à 1 à 6 atomes de carbone, utilisables comme inhibiteurs de l'agrégation plaquettaire.
Feigen Larry P.
Griffin Martin John
G.d. Searle & Co.
Osler Hoskin & Harcourt Llp
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