Transdermal compositions containing levosimendan

A - Human Necessities – 61 – K

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Details

A61K 31/50 (2006.01) A61K 9/00 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2259194

Transdermal administration of levosimendan or (-)-[[4-(1,4,5,6-tetrahydro- 4methyl-6-oxo-3- pyridazinyl)phenyl]hydrazono]propanedinitrile or a pharmaceutically acceptable salt thereof is disclosed. Transdermal preparations of levosimendan can be in the form of e.g. ointment, emulsion, lotion, solution, gel, cream, patch or transdermal delivery device including iontophoretic device.

L'invention concerne l'administration transdermique de lévosimendane ou de (-)-[[4-(1,4,5,6-tétrahydro-4-méthyl-6-oxo-3-pyridazinyl)phényl]hydrazono]propanedinitrile, ou d'un sel pharmaceutiquement acceptable de cette composition. Les préparations transdermiques de lévosimendane peuvent se présenter sous la forme d'un onguent, d'une émulsion, d'une lotion, d'une solution, d'un gel, d'une crème, d'une bande adhésive ou d'un dispositif d'administration transdermique, y compris un dispositif ionophorétique.

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