Transdermal delivery of...

Details Transdermal delivery of... Transdermal delivery of...

A - Human Necessities

61

K

167/209

A61K 31/55 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2026293

TRANSDERMAL DELIVERY OF (+) (2S, 3S)-3-ACETOXY-8-CHLORO-5-(2- DIMETHYLAMINOETHYL)-2,3-DIHYDRO-2-(4-METHOXYPHENYL)-1,5- BENZOTHIAZEPIN-4-(5H)-ONE Abstract of the Disclosure A method for treating angina, epilepsy and hypertension by achieving vasodilation, anti-angina or anti- convulsant effect in a patient is described. The method involves transdermally administering to a patient in need of vasodilation or anti-convulsant effect the compound known as (+)(2S,3S)-3-acetoxy-8-chloro-5-(2-dimethylaminoethyl)-2,3- dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4-(5H)-one in an amount sufficient to achieve desired systemic vasodilation, anti-angina or anti-convulsant levels of the compound.

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