Transdermal delivery of active drugs

Details Transdermal delivery of active drugs Transdermal delivery of active drugs

A - Human Necessities

61

K

A61K 31/21 (2006.01) A61K 9/70 (2006.01)

Patent

CA 2120054

ABSTRACT OF THE DISCLOSURE A transdermal delivery system is described, including a backing layer having coated thereon an active drug-containing adhesive layer which includes (a) an acrylic-based adhesive which is self-crosslinking at a temperature of from about 20°C to about 65°C and (b) an active drug. A method for manufacturing a transdermal delivery system is also described, including (A) mixing an active drug with an acrylic-based adhesive solution which is self-crosslinking at a temperature of from about 20°C to about 65°C to form an active drug-adhesive mixture, (B) forming a coating of the active drug-adhesive mixture on a backing layer, and (C) drying the coating to form an active drug- containing adhesive layer. Examples of the active drug include nitroglycerin and estradiol. 43

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