A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 31/135 (2006.01) A61K 31/18 (2006.01) A61K 31/505 (2006.01) A61K 31/55 (2006.01) A61K 47/12 (2006.01)
Patent
CA 2252772
Solubilization enhancer compositions are provided which facilitate transdermal administration of basic drugs from transdermal systems composed of nonpolar adhesive materials. Preferred solubilization enhancer compositions are comprised of liquid, isomeric acid mixtures such as oleic acid dimer. The invention also relates to novel transdermal systems, drug reservoirs, formulations, and methods of drug administration, in which the disclosed solubilization enhancer compositions are used.
L'invention concerne des compositions stimulant la solubilisation, ces compositions facilitant en outre l'administration transdermique de médicaments de base à partir de systèmes transdermiques composés de matières adhésives non polaires. Les compositions stimulant la solubilisation préférées renferment du liquide et des mélanges isomères acides, tel que le dimère d'acide oléique. L'invention concerne également de nouveaux systèmes transdermiques, des réservoirs contenant des médicaments, des formulations, et des procédés d'administration de médicaments qui utilisent les compositions stimulant la solubilisation susmentionnées.
Audett Jay
Bailey Susan E.
Cygnus Inc.
Dimock Stratton Llp
Ortho-Mcneil Pharmaceutical Inc.
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