A - Human Necessities – 61 – J
Patent
A - Human Necessities
61
J
167/159
A61J 3/00 (2006.01) A61K 9/70 (2006.01) A61K 31/12 (2006.01) A61K 31/335 (2006.01) A61K 47/08 (2006.01) A61K 47/22 (2006.01) A61L 9/04 (2006.01)
Patent
CA 1312281
- 36 - ABSTRACT OF INVENTION The rate of absorption of a physiologically active agent across skin and body membranes of animals and humans is increased by adding to a composition con- taining the active agent a lactone or a cyclic ketone of the formula (I) or a cyclic anhydride or ester of formula (II). Image Formula I Formula II wherein m+n are integers having a value from 1 to 20 with the proviso that m+n is at least 11 and not greater than 25, p is an integer having a value of 0 or 1, q is an integer having a value of 0 or 1, and R is hydrogen or an alkyl group having from 1 to 6 car- bon atoms. And as for a cyclic anhydride or ester, x is an integer having a value of 0 or 1 to 20, y is an integer having a value of 0 or 1 and z is an integer having a value of 0 or 1.
524372
Bentley Pharmaceuticals Inc.
Goudreau Gage Dubuc
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