A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/702 (2006.01) A61K 31/715 (2006.01) A61K 31/727 (2006.01) A61M 37/00 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2735983
The present invention relates to a system for facilitating transdermal delivery of oligosaccharides comprising an apparatus that generates micro-channels in the skin of a subject and a skin patch comprising a pharmaceutical composition com-prising as an active agent an oligosaccharide. Particularly, the composition comprises an oligosaccharide of 5-20 monosaccharide units, such as a pentasaccharide, which exerts anticoagulant activity. The system is capable of delivering the oligosaccharides into the blood circulation for treating thromboembolic diseases.
La présente invention concerne un système facilitant la libération transdermique doligosaccharides. Le système comprend un appareil qui génère des microcanaux dans la peau dun sujet, et un timbre cutané comprenant une composition pharmaceutique incluant, en tant quagent actif, un oligosaccharide. En particulier, la composition comprend un oligosaccharide comportant 5 à 20 unités de monosaccharide, tel qu'un pentasaccharide, qui a un effet anticoagulant. Le système permet de libérer les oligosaccharides dans le flux sanguin pour traiter les maladies thrombo-emboliques.
Levin Galit
Mazooz Galit
Sacks Hagit
Stern Meir
Ridout & Maybee Llp
Transpharma Medical Ltd.
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