A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/39 (2006.01) A61K 9/00 (2006.01) A61K 9/16 (2006.01) A61K 39/05 (2006.01) A61K 39/102 (2006.01) A61K 39/145 (2006.01) A61K 39/29 (2006.01)
Patent
CA 2312900
A method for enhancing the immune response to a selected antigen is disclosed. The method entails delivering a particulate adjuvant composition transdermally, preferably using a needleless syringe system. Also described are methods for forming crystalline particles from pharmaceutical compositions and then delivering the same to a subject. The crystallized compositions are particularly suitable for transdermal vaccine delivery using a needleless syringe system.
L'invention porte sur un procédé améliorant la réponse immunitaire vis à vis d'un antigène donné consistant à administrer par voie transdermique une composition d'adjuvant particulaire, de préférence à l'aide de seringues sans aiguille. L'invention porte également sur un procédé de formation de particules cristallines à partir de préparations pharmaceutiques et d'administration desdites particules à un sujet. Ces préparations cristallisées sont particulièrement adaptées à l'administration de vaccins à l'aide de seringues sans aiguille.
Chen Dexiang
Drape Robert J.
Sarphie David
Swain William F.
Widera Georg J.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Powderject Vaccines Inc.
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