Transdermal delivery system for polynucleotides

Details Transdermal delivery system for polynucleotides Transdermal delivery system for polynucleotides

A - Human Necessities

61

N

A61N 1/30 (2006.01) A61N 1/32 (2006.01)

Patent

CA 2554322

The present invention relates to a system for intradermal or transdermal delivery of oligonucleotides or polynucleotides and to methods of use thereof. Particularly, the present invention relates to a system comprising an apparatus that generates micro-channels in the skin of a subject in conjunction with a pharmaceutical composition comprising an oligonucleotide or polynucleotide, wherein the oligonucleotide or polynucleotide can be delivered into the organism through the micro-channels. The system and methods of the present invention achieve expression of target proteins encoded by the polynucleotides, and hence are useful in immunization and gene therapy.

La présente invention se rapporte à un système permettant l'administration intradermique ou transdermique d'oligonucléotides ou de polynucléotides ainsi qu'à leur procédé de mise en oeuvre. La présente invention se rapporte notamment à un système comportant un appareil qui produit des microcanaux dans la peau du sujet conjointement avec une composition pharmaceutique comportant un oligonucléotide ou un polynucléotide, l'oligonucléotide ou le polynucléotide pouvant être administré à l'organisme par l'intermédiaire des microcanaux. Le système et les procédés selon la présente invention permettent assurer l'expression de protéines cibles codées par les polynucléotides, et trouvent application dans l'immunisation et la thérapie génique.

Affiliated with

Also associated with

Rating

Transdermal delivery system for polynucleotides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transdermal delivery system for polynucleotides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transdermal delivery system for polynucleotides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2018058