Transdermal drug delivery devices comprising a polyurethane...

A - Human Necessities – 61 – K

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Details

A61K 9/70 (2006.01) A61K 47/34 (2006.01)

Patent

CA 2367100

The present invention relates to the field of transdermal drug delivery. More specifically, the present invention relates to drug reservoir materials for use in transdermal drug delivery devices. The drug reservoirs of the present invention comprise a polyurethane polymer which can be processed at temperatures below those which cause degradation of temperature sensitive drugs and/or excipients. The present invention is also directed to tailoring the release characteristics of the polyurethane material to accommodate a range of suitable drugs to be delivered from the transdermal drug delivery device and/or provide a range of delivery rates for a particular drug.

La présente invention concerne généralement le domaine de l'administration transdermale de médicaments, et plus particulièrement des matériaux réservoirs de médicaments destinés à des dispositifs d'administration transdermale de médicaments. Les réservoirs de médicaments de la présente invention comporte un polymère de polyuréthane qui se prête au traitement à des températures inférieures à celles qui provoquent la dégradation des médicaments et/ou excipients thermosensibles. L'invention concerne également l'adaptation des caractéristiques de libération du matériau en polyuréthane de façon à admettre toute une gamme de médicaments appropriés à faire libérer par le dispositif d'administration transdermale de médicaments et/ou à autoriser une multiplicité de débits de libération pour un médicament particulier.

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