A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01)
Patent
CA 2620160
The present invention provides transdermal drug delivery devices (i.e., patches) comprising O-desmethylvenlafaxine (ODV), a selective serotonin and norepinephrine re-uptake inhibitor, or a pharmaceutically acceptable salt thereof, which, among other, offer the advantage of eliminating or reducing the adverse side effects associated with the oral administration of ODV. Also provided are methods of preparing and using these transdermal delivery systems for the treatment of depression, anxiety disorders, vasomotor symptoms and pain.
La présente invention se rapporte à des dispositifs d'administration transdermique de médicaments (timbres), qui contiennent de la O-desméthylvenlafaxine (ODV), une sérotonine sélective et un inhibiteur du recaptage de la norépinéphrine, ou un sel pharmaceutiquement acceptable de la ODV. Les dispositifs selon l'invention présentent notamment l'avantage d'éliminer ou de réduire les effets secondaires indésirables associés à l'administration orale de ODV. L'invention a également trait à des procédés permettant de préparer lesdits systèmes d'administration transdermique et de les utiliser pour traiter la dépression, les troubles anxieux, les symptômes vasomoteurs et la douleur.
Shah Syed M.
Tatapudy Rao
Torys Llp
Wyeth
LandOfFree
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