Transdermal estradiol delivery system

A - Human Necessities – 61 – L

Patent

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167/159, 167/192

A61L 15/58 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01) A61L 15/24 (2006.01)

Patent

CA 1338819

A pressure-sensitive adhesive sheet material for delivering estradiol to skin, the sheet material comprising a backing with a layer of a pressure-sensitive adhesive adjacent thereto, said pressure-sensitive adhesive layer comprising a pressure-sensitive adhesive polymer, two or more skin penetration-enhancing ingredients and estradiol. The sheet material is useful for systemic treatment of conditions associated with estradiol deficiency. Methods of using such adhesive sheet material are also described.

594966

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