Transdermal iontophoretic delivery of...

A - Human Necessities – 61 – K

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A61K 31/496 (2006.01) A61N 1/30 (2006.01) A61P 25/00 (2006.01) A61P 25/16 (2006.01)

Patent

CA 2558113

The use of at least one compound of the general formula wherein R is defined herein, and pharmaceutically acceptable salts and prodrugs thereof; for the manufacture of an lontophoretic device for the treatment of Parkinson's disease and restless leg syndrome. The invention is further related to iontophoretic systems and to cartridges and kits containing the iontophoretic system combined with one or more cartridges containing a compound of formula I, and to cartridges containing a compound of formula I.

L'invention concerne l'utilisation d'au moins un composé de formule générale (I) dans laquelle R est tel que défini dans la description, et des sels pharmaceutiquement acceptables et des promédicaments de ce composé, pour la fabrication d'un dispositif iontophorétique pour le traitement de la maladie de Parkinson et du syndrome des jambes sans repos. L'invention concerne en outre des systèmes iontophorétiques, ainsi que des cartouches et des kits contenant ledit système iontophorétique, combiné avec une ou plusieurs cartouches contenant un composé de formule (I). L'invention concerne également les cartouches contenant un composé de formule (I).

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