Transdermal patch

Details Transdermal patch Transdermal patch

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61M 37/00 (2006.01)

Patent

CA 2245366

Transdermal patches are disclosed, including a backing layer, a liner layer, and a monolithic adhesive and drug-containing layer between the backing layer and the liner layer. The drug-containing adhesive layer includes polyisobutylene, a plasticizer for the polyisobutylene in which the ratio of the plasticizer and the polyisobutylene is less than about 0.8 and at least 5% of a filler. The drug so utilized is moderately soluble in the plasticizer.

Divulgation concernant des timbres transdermiques, composés d'une couche de support, d'une couche de revêtement, d'une couche adhésive monolithique et d'une couche renfermant un médicament entre la couche de support et la couche de revêtement. La couche adhésive contenant le médicament renferme du polyisobutylène, un plastifiant pour le polyisobutylène - le rapport plastifiant sur polyisobutylène étant inférieur à environ 0,8 -, et au moins 5 % d'une charge. Le médicament ainsi utilisé est modérément soluble dans le plastifiant.

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