Transdermal patch incorporating active agent migration...

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01)

Patent

CA 2531504

Devices (100) for administration of one or more active agents to the skin or mucosa of a host are formed in the nature of a double-disk patch (100). One outer layer (110) functions as the primary adhesive layer for adhering the patch (100) to the host. The other inner layer (122) contains at least one active agent to be administered to the host. The inner layer (122) is bonded to the outer layer (110) through an opening (114) provided in an interposed active agent impermeable release layer (104). The release layer (104) separates a circumferential portion of the active agent containing inner layer (122) from the outer adhesive layer (220) to inhibit migration of the active agent therebetween.

L'invention concerne des dispositifs (100) pour l'administration d'un ou plusieurs agents actifs sur la peau ou la muqueuse, se présentant sous la forme de timbre à double disque (100). Une couche externe (110) tient lieu de couche adhésive primaire pour l'adhésion du timbre (100). La couche interne (122) comporte au moins un agent actif destiné à être administré. Elle (122) est liée à la couche externe (110) par une ouverture (114) se trouvant dans une couche imperméable de libération d'agent actif intercalée (104). La couche de libération (104) sépare une partie circonférentielle de la couche interne renfermant l'agent actif (122) par rapport à la couche adhésive externe (220) pour inhiber la migration de l'agent actif entre les deux.

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