Transdermal pharmaceutical formulation for minimizing skin...

A - Human Necessities – 61 – K

Patent

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A61K 9/06 (2006.01) A61K 47/10 (2006.01)

Patent

CA 2538856

This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the user. The novel formulation includes at least one pharmacologically active ingredient, and a solvent system having a monoalkylether of diethylene gycol and a gycol present in specified ratios, and a mixture of water and alcohol. The invention also relates to a method for inhibiting or delaying crystallization of an active agent in a pharmaceutical formulation.

L'invention concerne une nouvelle formulation pharmaceutique transdermique ou transmuqueuse qui permet de réduire les risques de contamination et de transfert sur les habits de l'utilisateur. Cette nouvelle formulation comprend au moins un ingrédient pharmacologiquement actif, un système de solvant renfermant un monoalkyléther de diéthylène glycol et un glycol dans des proportions spécifiées ainsi qu'un mélange d'eau et d'alcool. L'invention concerne également un procédé permettant d'inhiber ou de retarder la cristallisation d'un agent actif de la formulation pharmaceutique.

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