A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 31/4465 (2006.01) A61M 37/00 (2006.01) A61P 7/02 (2006.01)
Patent
CA 2755569
The present invention provides a titratable transdermal drug delivery system comprising an effective dose of an antithrombotic agent, such as tirofiban, or a pharmaceutically acceptable salt thereof. The dosage of the drug delivered is proportional to the size of the patch applied and achieves 60-85% platelet inhibition. The system enables and individualized treatment for patients. Also provided are methods for the treatment of various disorders where platelet inhibition is desired.
La présente invention porte sur un système d'administration de médicament transdermique titrable comprenant une dose efficace d'un agent anti-thrombotique, tel que le tirofiban, ou un sel pharmaceutiquement acceptable de celui-ci. Le dosage du médicament administré est proportionnel à la dimension du timbre transdermique appliqué et poussent à une inhibition de plaquette de 60 à 85 %. Le système permet un traitement individualisé pour des patients. L'invention porte également sur des procédés de traitement de divers troubles pour lesquels on souhaite une inhibition des plaquettes.
Friesen Albert D.
Reimer Dawson James
Thomas George Roby
Medicure International Inc.
Ridout & Maybee Llp
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