Transdermal systems having control delivery system

Details Transdermal systems having control delivery system Transdermal systems having control delivery system

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61F 13/02 (2006.01) A61K 31/00 (2006.01) A61L 15/00 (2006.01)

Patent

CA 2598308

Transdermal delivery systems are disclosed including a backing layer (2), a polymer membrane (16) within the backing layer, an adhesive layer (14) for attaching the delivery system to the patient~s skin or mucosa, and a releasable layer (12) covering the adhesive layer prior to use, the polymer membrane impregnated with sufficient fluid medium to alter the rate of transmission of an active agent through the polymer membrane, with the amount of fluid medium being greater than the amount retained by the fluid membrane upon drying.

L'invention concerne des systèmes d'administration transdermiques comprenant une couche support (2), une membrane polymère (16) comprise dans la couche support, une couche adhésive (14) permettant de fixer le système d'administration à la peau ou la muqueuse du patient et une couche amovible (12) couvrant la couche adhésive avant l'utilisation, la membrane polymère étant imprégnée de milieu fluidique suffisant pour modifier la vitesse de transmission d'un agent actif à travers la membrane polymère, la quantité de milieu fluidique étant supérieure à la quantité retenue par la membrane fluidique au moment du séchage.

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