Transdermal therapeutic system comprising active ingredient...

Details Transdermal therapeutic system comprising active ingredient... Transdermal therapeutic system comprising active ingredient...

A - Human Necessities

61

K

A61K 9/70 (2006.01)

Patent

CA 2652216

The invention relates to a transdermal therapeutic system, preferably as transdermal patch, which has an active ingredient-containing matrix which consists substantially of a water-insoluble base material such as, for example, rubber and synthetic polymers, into which water-soluble and/or water-swellable inclusion bodies, e.g. composed of polyvinyl alcohol or polyethylene glycol, which comprise micronized or nanoscale active ingredient particles are incorporated.

L'invention concerne un système thérapeutique percutané, de préférence sous la forme d'un timbre percutané, qui présente une matrice contenant un principe actif, essentiellement constituée d'un matériau de base pratiquement insoluble dans l'eau, par exemple du caoutchouc et des polymères synthétiques, dans lequel sont incorporés des corps d'inclusion solubles dans l'eau et/ou gonflant dans l'eau, par exemple en alcool polyvinylique ou en polyéthylène glycol, qui contiennent des particules micronisées ou des nanoparticules du principe actif.

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