Transdermal therapeutic system containing hormones and...

Details Transdermal therapeutic system containing hormones and... Transdermal therapeutic system containing hormones and...

A - Human Necessities

61

K

A61K 31/567 (2006.01) A61K 9/70 (2006.01) A61K 31/565 (2006.01)

Patent

CA 2335582

A transdermal therapeutic system in plaster form for controlled release of oestradiol in combination with norethisterone acetate, comprising a backing layer, a reservoir supersaturated with active ingredients which is attached to said backing layer and prepared using polyacrylate pressure-sensitive adhesives and crystallization inhibitors, and a detachable protective layer, is characterized in that the crystallization inhibitor is an amino-containing polymer.

Système thérapeutique transdermique sous forme de pansement, destiné à l'administration régulée d'oestradiol en combinaison avec de l'acétate de noréthistérone. Ledit système comporte une couche support, un réservoir attaché à cette dernière et saturé de principes actifs, qui est préparé sur la base d'adhésif de contact polyacrylate et d'inhibiteurs de cristallisation, et une couche de protection pouvant être enlevée et réappliquée plusieurs fois. Ce système est caractérisé en ce que l'inhibiteur de cristallisation est un polymère contenant un groupe amino.

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