A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/70 (2006.01) A61K 47/02 (2006.01)
Patent
CA 2415658
The invention relates to a transdermal therapeutic system comprising a surface layer which is impervious with respect to an active ingredient; a self- adherent matrix layer or a plurality of matrix layers, wherein the exposed matrix layer is, at least self-adherent when the system is applied. Said system also comprises a pull-off protective coating, whereby the matrix layer(s) contains(s) one or more active ingredients and/or one or more biologically active substances and highly dispersed silicon dioxide. Said system contains silicon dioxide in order to increase skin permeation.
L'invention concerne un système thérapeutique transdermique comprenant une couche de recouvrement imperméable au principe actif, une ou plusieurs couches matricielles autocollantes, parmi lesquelles au moins la couche matricielle dégagée lors de l'application du système est autocollante, et une couche de protection amovible. La ou les couches matricielles contiennent un ou plusieurs principes actifs et/ou une ou plusieurs autres substances biologiquement actives ainsi que du dioxyde de silicium fortement dispersé, ce dernier servant à augmenter la perméation cutanée.
Klokkers Karin
Kramer Kai-Thomas
Wilhelm Martina
Hexal Age
Sim & Mcburney
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