A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/215 (2006.01) A61K 9/70 (2006.01) A61K 31/135 (2006.01) A61K 31/216 (2006.01) A61L 15/44 (2006.01)
Patent
CA 2311354
The invention relates to a transdermal therapeutic system (TTS) for transcutaneous administration of oxybutynin over a period of several days, in addition to a method for the production thereof without the use of solvents. The TTS contains a matrix mass containing oxybutynin in the form of a self-adhesive layer. Said matrix mass consists of (meth)-acrylic polymers containing ammoniac groups, at least one citric acid ester and 5-25 wt. % oxybutynin.
L'invention concerne un système thérapeutique transdermique (TTS) destiné à l'administration transcutanée d'oxybutynine pendant plusieurs jours. L'invention concerne également son procédé de production sans utiliser de solvants. Le TTS contient une matière matrice contenant de l'oxybutynine et se présentant sous la forme d'une couche autocollante. La matière matrice est constituée de polymères (méth)-acryliques contenant des groupes ammoniacaux, d'au moins un ester d'acide citrique et de 5 à 25 % en poids d'oxybutynine.
Arth Christoph
Kollmeyer-Seeger Andreas
Rimpler Stephan
Wolff Hans-Michael
Robic
Schwarz Pharma Ag
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