Transdermal warfarin-containing delivery system

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/70 (2006.01) A61K 31/37 (2006.01)

Patent

CA 2534238

Composition of matter for application to a body surface or membrane to administer warfarin by permeation through the body surface or membrane, the composition comprising warfarin to be administered, at a therapeutically effective rate, alone or in combination with a permeation enhancer or mixture. Also disclosed are drug delivery devices containing the warfarin or warfarin and enhancer composition and methods for the transdermal administration of the warfarin and warfarin/enhancer composition.

La présente invention concerne une composition destinée à être appliquée sur une surface corporelle ou une membrane afin d'administrer de la warfarine par pénétration à travers la surface corporelle ou la membrane, la composition comprenant de la warfarine à administrer, de façon à obtenir une efficacité thérapeutique, seule ou en combinaison avec un agent d'amélioration de pénétration ou un mélange. L'invention a également pour objet des dispositifs d'administration d'agent pharmaceutique contenant la warfarine ou de la warfarine et une composition d'amélioration, ainsi que des procédés pour administrer par voie transdermique de la warfarine et un mélange warfarine/composition d'amélioration.

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