Transdermally deliverable buprenorphine prodrugs and...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 489/02 (2006.01) A61K 31/439 (2006.01) A61P 23/00 (2006.01)

Patent

CA 2663515

Described herein are prodrugs of the opioid buprenorphine, methods of making them, formulations comprising these prodrugs, and methods of using them. One embodiment described herein relates to the transdermal administration of a buprenorphine prodrug in an abuse-resistant formulation for treating and preventing diseases and/or disorders.

L'invention concerne des promédicaments d'opioïdes, des procédés de fabrication de promédicaments d'opioïdes, des formulations comprenant des promédicaments d'opioïdes et des procédés d'utilisation de promédicaments d'opioïdes. Un mode de réalisation décrit ici concerne l'administration transdermique d'un promédicament de la buprénorphine dans une formulation empêchant l'usage abusif de celui-ci pour traiter et prévenir des maladies et/ou des troubles.

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