A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 25/34 (2006.01) A61F 13/02 (2006.01) A61K 9/70 (2006.01) A61K 47/18 (2006.01) A61K 47/32 (2006.01) A61L 15/16 (2006.01)
Patent
CA 2340120
An aspirin formulation suitable for transdermal delivery has powdered aspirin dissolved in relatively high concentrations in a solution composed of a pharmaceutically acceptable solvent and an organic amine a. The primary solvent is preferably an organic hydroxy compound having good transdermal propellant characteristics. The resulting aspirin solution is nonirritating to the skin and exhibits good stability over the useful life of a transdermal delivery patch. A patch suitable for delivering the aspirin solution to the skin of a patient is also described.
Formulation d'aspirine pouvant être administrée par voie transdermique et consistant en de l'aspirine en poudre dissoute en concentrations relativement élevées dans une solution composée d'un solvant acceptable sur le plan pharmaceutique et d'une amine organique. Ce solvant primaire est, de préférence, un composé hydroxy organique présentant des caractéristiques avantageuses de propulsion transdermique. La solution d'aspirine obtenue n'est pas irritante pour la peau et est stable pendant la durée de vie utile d'un patch d'administration transdermique. L'invention concerne également un patch permettant d'appliquer la solution d'aspirine à la peau du patient.
Galat Alexander
Johnson Ernest Peter
LandOfFree
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