Transduced fibroblasts and uses therefor

C - Chemistry – Metallurgy – 12 – N

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167/104, 195/1.3

C12N 15/12 (2006.01) A61K 35/12 (2006.01) A61K 48/00 (2006.01) C07K 14/635 (2006.01) C12N 5/10 (2006.01) C12N 15/65 (2006.01) C12N 15/867 (2006.01)

Patent

CA 1341311

Fibroblasts transduced with genetic material encoding a polypeptide or protein of interest and, optionally, a selectable marker, as well as methods for making and using the transduced fibroblasts. Such fibroblasts are useful in delivering the encoded polypeptide or protein, such as an enzyme, a hormone or a drug, to an individual who has had a graft or implant of the transduced cells.

577028

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