Transductin-1 and transductin-2 and applications to...

Details Transductin-1 and transductin-2 and applications to... Transductin-1 and transductin-2 and applications to...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C07K 16/28 (2006.01) C12N 5/12 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2457303

The invention provides an isolated or purified nucleic acid molecule consisting essentially of the nucleotide sequence encoding transductin-2 (TDC2), related and derivative nucleic acid molecules, vectors comprising the isolated or purified nucleic acid sequences, cells comprising such vectors, polypeptides encoded by the nucleic acid molecules, monoclonal antibodies and cell lines producing the monoclonal antibodies. The invention also provides methods of treating, prognosticating and monitoring hearing loss.

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