C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 5/09 (2006.01) A61K 38/02 (2006.01) A61K 38/06 (2006.01) A61K 38/07 (2006.01) A61K 38/08 (2006.01) A61K 39/00 (2006.01) A61K 47/48 (2006.01) A61K 48/00 (2006.01) C07K 5/103 (2006.01) C07K 7/06 (2006.01) C07K 14/00 (2006.01) C12N 15/88 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2470152
The invention provides a peptide having at least 3 amino acids comprising an amino acid sequence selected from a) X1SM [SEQ.ID.NO.:1] b) LX2HK [SEQ.ID.NO.:2] c) PSGX3ARA [SEQ.ID.NO.:9] d) SX4RSMNF [SEQ.ID.NO.:16] e) LX5HKSMP [SEQ.ID.NO.:18] in which X is a basic amino acid residue, X1 is Q or P, X2 is A or T, X3 is an acidic amino acid residue and X4 is P or Q. the invention further provides non-viral cell-targeting vector complexes and methods associated therewith.
L'invention concerne un peptide présentant au moins 3 amino acides comprenant une séquence d'amino acides sélectionnée dans a) X?1¿SM [SEQ.ID.NO.:1] b) LX?2¿HK [SEQ.ID.NO.:2] c) PSGX?3¿ARA [SEQ.ID.NO.:9] d) SX?4¿RSMNF [SEQ.ID.NO.:16] e) LX?5¿HKSMP [SEQ.ID.NO.:18], où X?1¿ désigne un résidu amino acide basique, X?2¿ désigne Q ou P, X?3¿ désigne A ou T, X?4¿ désigne un résidu amino acide et X?5¿ désigne P ou Q. L'invention concerne également des complexes de vecteur de ciblage de cellules non-viraux et des procédés associés.
Hart Stephen Lewis
Writer Michele
Ich Productions Limited
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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