Transfection kinetics and structural promoters

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12N 15/87 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2464464

The invention features methods of analyzing the kinetics properties of transfection reactions. Also featured are methods for creating structural promoters which are effectively unregulated by enhancers and repressors. The structural promoters are significantly more active than the native promoter sequences upon which they are based.

La présente invention concerne des procédés d'analyse des propriétés cinétiques des réactions de transfection, ainsi que des procédés de création de promoteurs de structure qui sont efficacement non régulés par des activateurs et des répresseurs. Les promoteurs de structure sont significativement plus actifs que les séquences de promoteur natif sur lesquelles ils sont basés.

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