Transfer hydrogenation process and catalyst

Details Transfer hydrogenation process and catalyst Transfer hydrogenation process and catalyst

B - Operations, Transporting

01

J

B01J 31/22 (2006.01) B01J 31/18 (2006.01) C07B 31/00 (2006.01) C07C 29/143 (2006.01) C07C 209/52 (2006.01) C07F 15/00 (2006.01) C07F 17/00 (2006.01)

Patent

CA 2284777

A catalytic transfer hydrogenation process is provided. The catalyst employed in the process is a metal cyclopentadienyl complex which is coordinated to defined bidentate ligands. Preferred metals include rhodium, ruthenium and iridium. Preferred bidentate ligands are diamines and aminoalcohols, particularly those comprising chiral centres. The hydrogen donor is advantageously a secondary alcohol or a mixture of triethylamine and formic acid. The process can be employed to transfer hydrogenate ketones and imines, which are preferably prochiral. Catalysts for use in such a process are also provided.

L'invention concerne un processus d'hydrogénation catalytique par transfert. Le catalyseur utilisé dans le processus est un complexe métallifère cyclopentadiényle coordonné avec des ligands bidentés déterminés. Des métaux préférés incluent le rhodium, le ruthénium et l'iridium. Des ligands bidentés préférés sont des diamines et des amino-alcools, en particulier ceux comprenant des centres chiraux. Le donneur d'hydrogène est utilement un alcool secondaire ou un mélange de triéthylamine et d'acide formique. Le processus peut être utilisé pour hydrogéner par transfert des cétones et des imines, lesquels sont prochiraux de préférence. L'invention concerne en outre des catalyseurs pouvant être utilisés pour la réalisation dudit processus.

Affiliated with

Also associated with

Rating

Transfer hydrogenation process and catalyst does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Transfer hydrogenation process and catalyst, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Transfer hydrogenation process and catalyst will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1980528