C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 19/00 (2006.01) C07K 14/76 (2006.01) C07K 14/79 (2006.01) C12N 15/62 (2006.01) C40B 30/04 (2006.01) C40B 40/10 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01) C12N 1/15 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01)
Patent
CA 2673085
Fusion proteins comprising a transferrin moiety and integrin binding domain and peptide libraries thereof are disclosed. The present invention includes a method of screening transferrin and integrin peptide libraries displayed in fusion proteins expressed by host cells. The fusion proteins of the present invention include transferrin fusion proteins capable of expression in yeast.
La présente invention concerne des protéines hybrides comprenant un fragment de transferrine et un domaine de liaison à l'intégrine et des bibliothèques peptidiques de celles-ci. La présente invention comprend un procédé de criblage de bibliothèques peptidiques de transferrine et d'intégrine montrées dans des protéines hybrides exprimées par des cellules hôtes. Les protéines hybrides de la présente invention comprennent des protéines hybrides de transferrine capables d'une expression dans des levures.
Turner Andrew John
Wang Baiyang
Biorexis Pharmaceutical Corporation
Smart & Biggar
LandOfFree
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