Transferrin receptor genes of moraxella

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/11 (2006.01) A61K 39/02 (2006.01) A61K 48/00 (2006.01) C07K 14/21 (2006.01) C07K 14/22 (2006.01) C07K 14/79 (2006.01) C12N 15/31 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2325330

Purified and isolated nucleic acid molecules are provided which encode Tbp2 proteins of M. catarrhalis strains M35, 3 and LES1. The nucleic acid sequence may be used to produce recombinant Tbp2 proteins of the strain of Moraxella free of other proteins of the Moraxella strain for purposes of diagnostics and medical treatment. Furthermore, the nucleic acid molecules may be used in the diagnosis of infection.

L'invention concerne des molécules purifiées et isolées d'acides nucléiques codant pour les protéines Tbp2 des souches M35, 3 et LES1 de M. catarrhalis. La séquence d'acides nucléiques peut être utilisée pour produire des protéines recombinantes Tbp2 de la souche de Moraxella exemptes d'autres protéines de la souche de Moraxella et servant à des fins de diagnostic et de traitement médical. En outre, on peut utiliser les molécules d'acides nucléiques dans le diagnostic d'une infection.

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