Transgenic animal

A - Human Necessities – 01 – K

Patent

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Details

A01K 67/027 (2006.01) C07K 14/52 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2254949

The present invention relates to a novel transgenic mouse. It relates to providing transgenic animals which can not express endogenous osteoclastogenesis inhibitory factor, more specifically transgenic animals which will suffer from spontaneous metabolic bone disease, more specifically spontaneous osteoporosis. Further, a method of screening agents for preventing and/or treating metabolic bone diseases characterized by using transgenic animals of the present invention. The transgenic animals of the present invention are useful for research of bone metabolism or for animals for research of evaluation and screening of agents for preventing and/or treating metabolic bone diseases.

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