Transgenic animal allergy models and methods for their use

A - Human Necessities – 01 – K

Patent

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A01K 67/027 (2006.01) C07K 16/00 (2006.01) C12N 15/85 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2251263

Transgenic animals, especially mice, which constitutively express an antibody-type molecule encoded by the transgene and which has an IgE heavy chain constant region and is specific for a pre-defined antigen, provide an allergic reaction to that antigen without prior sensitization and are useful as allergy models.

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